Functional Coverage of the Human Genome by Existing Structures, Structural Genomics Targets and Homology Models
نویسندگان
چکیده
منابع مشابه
Functional Coverage of the Human Genome by Existing Structures, Structural Genomics Targets, and Homology Models
The bias in protein structure and function space resulting from experimental limitations and targeting of particular functional classes of proteins by structural biologists has long been recognized, but never continuously quantified. Using the Enzyme Commission and the Gene Ontology classifications as a reference frame, and integrating structure data from the Protein Data Bank (PDB), target seq...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2005
ISSN: 1553-734X,1553-7358
DOI: 10.1371/journal.pcbi.0010031.eor